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پاورپوینت در مورد Antibiotic use in critical care

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پاورپوینت در مورد Antibiotic use in critical care

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نوع فایل :  powerpoint (..ppt) ( قابل ويرايش و آماده پرينت )

تعداد اسلاید : 36 اسلاید

 قسمتی از متن powerpoint (..ppt) : 

Antibiotic use in critical care

Objectives

To discuss epidemiology of sepsis

To discuss principles of antibiotic use

To explore effects of critical illness on pharmacokinetics of commonly used antibiotics

To appreciate the burden of emerging multidrug resistant bacteria

To look at the role of novel biomarkers in guiding antibiotic therapy

My experience with antibiotics use

Sepsis top player: admissions to critical care

Antibiotics : in Top 5 of ICU spend

Sepsis

Sepsis, severe sepsis and septic shock remains a major cause of morbidity and mortality

Mortality for severe sepsis ≥5-fold higher than that for acute coronary syndrome or for stroke.

Incidence of sepsis requiring intensive care admission of 0.25–0.38 per 1000 population, suggesting ∼2 million admissions to critical care units alone.

The EPIC study, a point prevalence study performed in 1265 critical care units in 2009 evaluated 14414 patients estimated that over half the patients in the units were infected, more than 70% of them were on antibiotics and 62% of the microbiological isolates were gram negative bacteria.

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